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Cyclic AMP dynamics in the pancreatic β-cell

Insulin secretion from pancreatic β-cells is tightly regulated by glucose and other nutrients, hormones, and neural factors. The exocytosis of insulin granules is triggered by an elevation of the cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) and is further amplified by cyclic AMP (cAMP). Cyclic AMP...

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Bibliografiske detaljer
Hovedforfatter: Tengholm, Anders
Format: Artigo
Sprog:Inglês
Udgivet: Informa Healthcare 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497220/
https://ncbi.nlm.nih.gov/pubmed/22970724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03009734.2012.724732
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