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Glucose- and Hormone-Induced cAMP Oscillations in α- and β-Cells Within Intact Pancreatic Islets

OBJECTIVE: cAMP is a critical messenger for insulin and glucagon secretion from pancreatic β- and α-cells, respectively. Dispersed β-cells show cAMP oscillations, but the signaling kinetics in cells within intact islets of Langerhans is unknown. RESEARCH DESIGN AND METHODS: The subplasma-membrane cA...

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Detaylı Bibliyografya
Asıl Yazarlar: Tian, Geng, Sandler, Stellan, Gylfe, Erik, Tengholm, Anders
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292328/
https://ncbi.nlm.nih.gov/pubmed/21444924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1087
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