Glucose controls glucagon secretion by directly modulating cAMP in alpha cells

AIMS/HYPOTHESIS: Glucagon is critical for normal glucose homeostasis and aberrant secretion of the hormone aggravates dysregulated glucose control in diabetes. However, the mechanisms by which glucose controls glucagon secretion from pancreatic alpha cells remain elusive. The aim of this study was t...

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Bibliographic Details
Published in:Diabetologia
Main Authors: Yu, Qian, Shuai, Hongyan, Ahooghalandari, Parvin, Gylfe, Erik, Tengholm, Anders
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560012/
https://ncbi.nlm.nih.gov/pubmed/30953108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-019-4857-6
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