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Glucose controls glucagon secretion by directly modulating cAMP in alpha cells

AIMS/HYPOTHESIS: Glucagon is critical for normal glucose homeostasis and aberrant secretion of the hormone aggravates dysregulated glucose control in diabetes. However, the mechanisms by which glucose controls glucagon secretion from pancreatic alpha cells remain elusive. The aim of this study was t...

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Bibliografiske detaljer
Udgivet i:Diabetologia
Main Authors: Yu, Qian, Shuai, Hongyan, Ahooghalandari, Parvin, Gylfe, Erik, Tengholm, Anders
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560012/
https://ncbi.nlm.nih.gov/pubmed/30953108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-019-4857-6
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