Clinically Relevant Gram-Negative Resistance Mechanisms Have No Effect on the Efficacy of MC-1, a Novel Siderophore-Conjugated Monocarbam

The incidence of hospital-acquired infections with multidrug-resistant (MDR) Gram-negative pathogens is increasing at an alarming rate. Equally alarming is the overall lack of efficacious therapeutic options for clinicians, which is due primarily to the acquisition and development of various antibio...

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Main Authors: McPherson, Craig J., Aschenbrenner, Lisa M., Lacey, Brian M., Fahnoe, Kelly C., Lemmon, Margaret M., Finegan, Steven M., Tadakamalla, Baswanth, O'Donnell, John P., Mueller, John P., Tomaras, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497185/
https://ncbi.nlm.nih.gov/pubmed/23027195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01345-12
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