IFNγR signaling mediates alloreactive T-cell trafficking and GVHD

The clinical goal of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is to minimize GVHD while maintaining GvL. Here, we show that interferon γ receptor-deficient (IFNγR(−/−)) allogeneic Tconv, which possess normal alloreactivity and cytotoxicity, induce significantly less GVHD than w...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Choi, Jaebok, Ziga, Edward D., Ritchey, Julie, Collins, Lynne, Prior, Julie L., Cooper, Matthew L., Piwnica-Worms, David, DiPersio, John F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
Materias:
Transplantation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496960/
https://ncbi.nlm.nih.gov/pubmed/22972985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-403196
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares