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Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation

Allogeneic hematopoietic cell transplantation is often complicated by graft versus host disease (GvHD), primarily mediated through allo-reactive donor T cells in the donor stem cell graft. Enhancer of Zeste Homolog 2 (EZH2), a histone-lysine N-methyltransferase and a component of the Polycomb Repres...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Alahmari, Bader, Cooper, Matthew, Ziga, Edward, Ritchey, Julie, DiPersio, John F., Choi, Jaebok
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242356/
https://ncbi.nlm.nih.gov/pubmed/30452487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207609
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