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Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation
Allogeneic hematopoietic cell transplantation is often complicated by graft versus host disease (GvHD), primarily mediated through allo-reactive donor T cells in the donor stem cell graft. Enhancer of Zeste Homolog 2 (EZH2), a histone-lysine N-methyltransferase and a component of the Polycomb Repres...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6242356/ https://ncbi.nlm.nih.gov/pubmed/30452487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207609 |
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