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Mechanism of platelet dense granule biogenesis: study of cargo transport and function of Rab32 and Rab38 in a model system

Dense granules are important in platelet aggregation to form a hemostatic plug as evidenced by the increased bleeding time in mice and humans with dense granule deficiency. Dense granules also are targeted by antiplatelet agents because of their role in thrombus formation. Therefore, the molecular u...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ambrosio, Andrea L., Boyle, Judith A., Di Pietro, Santiago M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496959/
https://ncbi.nlm.nih.gov/pubmed/22927249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-420745
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