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Simple and sensitive assay for quantification of oseltamivir and its active metabolite oseltamivir carboxylate in human plasma using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry: improved applicability to pharmacokinetic study

Although liquid chromatography/electrospray ionization tandem mass spectrometry-based assays have been reported for the measurement of the antiviral oseltamivir (OS) in human samples, these assays either involve complicated sample pretreatment or lack sensitivity. Here we introduce a straightforward...

詳細記述

保存先:
書誌詳細
主要な著者: Hu, Zhe-Yi, Laizure, S. Casey, Meibohm, Bernd, Herring, Vanessa L., Parker, Robert B.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496839/
https://ncbi.nlm.nih.gov/pubmed/23000242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2012.08.029
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