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Transcriptome assembly and isoform expression level estimation from biased RNA-Seq reads
Motivation: RNA-Seq uses the high-throughput sequencing technology to identify and quantify transcriptome at an unprecedented high resolution and low cost. However, RNA-Seq reads are usually not uniformly distributed and biases in RNA-Seq data post great challenges in many applications including tra...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496342/ https://ncbi.nlm.nih.gov/pubmed/23060617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts559 |
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