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Transcriptome assembly and isoform expression level estimation from biased RNA-Seq reads

Motivation: RNA-Seq uses the high-throughput sequencing technology to identify and quantify transcriptome at an unprecedented high resolution and low cost. However, RNA-Seq reads are usually not uniformly distributed and biases in RNA-Seq data post great challenges in many applications including tra...

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Detalhes bibliográficos
Main Authors: Li, Wei, Jiang, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496342/
https://ncbi.nlm.nih.gov/pubmed/23060617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts559
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