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Semaphorin 7A Contributes to West Nile Virus Pathogenesis through TGF-β1/Smad6 Signaling

Semaphorin 7A (Sema7A) is a membrane-associated/secreted protein that plays an essential role in connecting the vertebrate neuronal and immune systems. However, the role of Sema7A has not been elucidated in viral pathogenesis. In this study, we show that abrogation of Sema7A protects mice from letha...

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Detalhes bibliográficos
Main Authors: Sultana, Hameeda, Neelakanta, Girish, Foellmer, Harald G., Montgomery, Ruth R., Anderson, John F., Koski, Raymond A., Medzhitov, Ruslan M., Fikrig, Erol
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496209/
https://ncbi.nlm.nih.gov/pubmed/22896629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201140
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