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Fusion loop peptide of the West Nile virus envelope protein is essential for pathogenesis and recognized by a therapeutic cross-reactive human monoclonal antibody
West Nile virus is an emerging pathogen that can cause fatal neurological disease. A recombinant human monoclonal antibody, mAb11, has been described as a candidate for the prevention and treatment of West Nile disease. Using a yeast surface display epitope mapping assay and neutralization escape mu...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690769/ https://ncbi.nlm.nih.gov/pubmed/19535627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900093 |
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