Fusion loop peptide of the West Nile virus envelope protein is essential for pathogenesis and recognized by a therapeutic cross-reactive human monoclonal antibody

West Nile virus is an emerging pathogen that can cause fatal neurological disease. A recombinant human monoclonal antibody, mAb11, has been described as a candidate for the prevention and treatment of West Nile disease. Using a yeast surface display epitope mapping assay and neutralization escape mu...

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Hlavní autoři: Sultana, Hameeda, Foellmer, Harald G., Neelakanta, Girish, Oliphant, Theodore, Engle, Michael, Ledizet, Michel, Krishnan, Manoj, Bonafe, Nathalie, Anthony, Karen G., Marasco, Wayne A., Kaplan, Paul, Montgomery, Ruth R., Diamond, Michael S., Koski, Raymond A., Fikrig, Erol
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690769/
https://ncbi.nlm.nih.gov/pubmed/19535627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900093
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