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IL-22 Signaling Contributes to West Nile Encephalitis Pathogenesis
The Th17 cytokine, IL-22, regulates host immune responses to extracellular pathogens. Whether IL-22 plays a role in viral infection, however, is poorly understood. We report here that Il22(−/−) mice were more resistant to lethal West Nile virus (WNV) encephalitis, but had similar viral loads in the...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429482/ https://ncbi.nlm.nih.gov/pubmed/22952908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044153 |
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