IL-10 Signaling Blockade Controls Murine West Nile Virus Infection

West Nile virus (WNV), a mosquito-borne single-stranded RNA flavivirus, can cause significant human morbidity and mortality. Our data show that interleukin-10 (IL-10) is dramatically elevated both in vitro and in vivo following WNV infection. Consistent with an etiologic role of IL-10 in WNV pathoge...

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Detalhes bibliográficos
Main Authors: Bai, Fengwei, Town, Terrence, Qian, Feng, Wang, Penghua, Kamanaka, Masahito, Connolly, Tarah M., Gate, David, Montgomery, Ruth R., Flavell, Richard A., Fikrig, Erol
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749443/
https://ncbi.nlm.nih.gov/pubmed/19816558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000610
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