Interleukin-17A Promotes CD8(+) T Cell Cytotoxicity To Facilitate West Nile Virus Clearance

CD8(+) T cells are crucial components of immunity and play a vital role in recovery from West Nile virus (WNV) infection. Here, we identify a previously unrecognized function of interleukin-17A (IL-17A) in inducing cytotoxic-mediator gene expression and promoting CD8(+) T cell cytotoxicity against W...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Acharya, Dhiraj, Wang, Penghua, Paul, Amber M., Dai, Jianfeng, Gate, David, Lowery, Jordan E., Stokic, Dobrivoje S., Leis, A. Arturo, Flavell, Richard A., Town, Terrence, Fikrig, Erol, Bai, Fengwei
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5165211/
https://ncbi.nlm.nih.gov/pubmed/27795421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01529-16
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