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A Paradoxical Role for Neutrophils in the Pathogenesis of West Nile Virus

Polymorphonuclear leukocytes (PMNs) are key in innate immunity, but their role in viral pathogenesis is incompletely understood. In infection due to West Nile virus (WNV), we found that expression of 2 PMNattracting chemokines, Cxcl1 and Cxcl2, was rapidly and dramatically elevated in macrophages. P...

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Detalhes bibliográficos
Main Authors: Bai, Fengwei, Kong, Kok-Fai, Dai, Jianfeng, Qian, Feng, Zhang, Lin, Brown, Charles R., Fikrig, Erol, Montgometry, Ruth R.
Formato: Artigo
Idioma:Inglês
Publicado em: The University of Chicago Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053000/
https://ncbi.nlm.nih.gov/pubmed/21050124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/657416
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