The Adjuvant LT-K63 Can Restore Delayed Maturation of Follicular Dendritic Cells and Poor Persistence of Both Protein- and Polysaccharide-Specific Antibody-Secreting Cells in Neonatal Mice

Ab responses in early life are low and short-lived; therefore, induction of protective immunity requires repeated vaccinations. One of the major limitations in early-life immunity is delayed maturation of follicular dendritic cells (FDCs), which play a central role in mediating the germinal center (...

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Bibliographische Detailangaben
Hauptverfasser: Bjarnarson, Stefania P., Adarna, Brenda C., Benonisson, Hreinn, Del Giudice, Giuseppe, Jonsdottir, Ingileif
Format: Artigo
Sprache:Inglês
Veröffentlicht: AAI 2012
Schlagworte:
Cellular Immunology and Immune Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496199/
https://ncbi.nlm.nih.gov/pubmed/22753937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200761
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