Intranasal Immunization with Pneumococcal Conjugate Vaccines with LT-K63, a Nontoxic Mutant of Heat-Labile Enterotoxin, as Adjuvant Rapidly Induces Protective Immunity against Lethal Pneumococcal Infections in Neonatal Mice

Immunization with pneumococcal polysaccharides (PPS) conjugated to tetanus toxoid (TT) (Pnc-TT) elicits protective immunity in an adult murine pneumococcal infection model. To assess immunogenicity and protective immunity in early life, neonatal (1 week old) and infant (3 weeks old) mice were immuni...

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Xehetasun bibliografikoak
Egile Nagusiak: Jakobsen, Håvard, Bjarnarson, Stefania, Del Giudice, Giuseppe, Moreau, Monique, Siegrist, Claire-Anne, Jonsdottir, Ingileif
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2002
Gaiak:
Microbial Immunity and Vaccines
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC127807/
https://ncbi.nlm.nih.gov/pubmed/11854231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1443-1452.2002
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