Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal Mice

Immaturity of the immune system contributes to poor vaccine responses in early life. Germinal center (GC) activation is limited due to poorly developed follicular dendritic cells (FDC), causing generation of few antibody-secreting cells (ASCs) with limited survival and transient antibody responses....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Immunol
Egile Nagusiak: Aradottir Pind, Audur Anna, Dubik, Magdalena, Thorsdottir, Sigrun, Meinke, Andreas, Harandi, Ali M., Holmgren, Jan, Del Giudice, Giuseppe, Jonsdottir, Ingileif, Bjarnarson, Stefania P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775194/
https://ncbi.nlm.nih.gov/pubmed/31616417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02214
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