Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal Mice

Immaturity of the immune system contributes to poor vaccine responses in early life. Germinal center (GC) activation is limited due to poorly developed follicular dendritic cells (FDC), causing generation of few antibody-secreting cells (ASCs) with limited survival and transient antibody responses....

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Aradottir Pind, Audur Anna, Dubik, Magdalena, Thorsdottir, Sigrun, Meinke, Andreas, Harandi, Ali M., Holmgren, Jan, Del Giudice, Giuseppe, Jonsdottir, Ingileif, Bjarnarson, Stefania P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2019
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775194/
https://ncbi.nlm.nih.gov/pubmed/31616417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02214
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