The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation

INTRODUCTION: Although a high frequency of androgen receptor (AR) expression in human breast cancers has been described, exploiting this knowledge for therapy has been challenging. This is in part because androgens can either inhibit or stimulate cell proliferation in pre-clinical models of breast c...

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Opis bibliograficzny
Główni autorzy: Garay, Joseph P, Karakas, Bedri, Abukhdeir, Abde M, Cosgrove, David P, Gustin, John P, Higgins, Michaela J, Konishi, Hiroyuki, Konishi, Yuko, Lauring, Josh, Mohseni, Morassa, Wang, Grace M, Jelovac, Danijela, Weeraratna, Ashani, Sherman Baust, Cheryl A, Morin, Patrice J, Toubaji, Antoun, Meeker, Alan, De Marzo, Angelo M, Lewis, Gloria, Subhawong, Andrea, Argani, Pedram, Park, Ben H
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2012
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496145/
https://ncbi.nlm.nih.gov/pubmed/22321971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3112
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