Tamoxifen-stimulated growth of breast cancer due to p21 loss

Tamoxifen is widely used for the treatment of hormonally responsive breast cancers. However, some resistant breast cancers develop a growth proliferative response to this drug, as evidenced by tumor regression upon its withdrawal. To elucidate the molecular mediators of this paradox, tissue samples...

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Detalhes bibliográficos
Main Authors: Abukhdeir, Abde M., Vitolo, Michele I., Argani, Pedram, De Marzo, Angelo M., Karakas, Bedri, Konishi, Hiroyuki, Gustin, John P., Lauring, Josh, Garay, Joseph P., Pendleton, Courtney, Konishi, Yuko, Blair, Brian G., Brenner, Keith, Garrett-Mayer, Elizabeth, Carraway, Hetty, Bachman, Kurtis E., Park, Ben Ho
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224203/
https://ncbi.nlm.nih.gov/pubmed/18162533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710887105
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