Tamoxifen-stimulated growth of breast cancer due to p21 loss

Tamoxifen is widely used for the treatment of hormonally responsive breast cancers. However, some resistant breast cancers develop a growth proliferative response to this drug, as evidenced by tumor regression upon its withdrawal. To elucidate the molecular mediators of this paradox, tissue samples...

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Bibliographic Details
Main Authors:	Abukhdeir, Abde M., Vitolo, Michele I., Argani, Pedram, De Marzo, Angelo M., Karakas, Bedri, Konishi, Hiroyuki, Gustin, John P., Lauring, Josh, Garay, Joseph P., Pendleton, Courtney, Konishi, Yuko, Blair, Brian G., Brenner, Keith, Garrett-Mayer, Elizabeth, Carraway, Hetty, Bachman, Kurtis E., Park, Ben Ho
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 2008
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2224203/ https://ncbi.nlm.nih.gov/pubmed/18162533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710887105
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Tamoxifen-stimulated growth of breast cancer due to p21 loss

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