Tamoxifen-stimulated growth of breast cancer due to p21 loss

Tamoxifen is widely used for the treatment of hormonally responsive breast cancers. However, some resistant breast cancers develop a growth proliferative response to this drug, as evidenced by tumor regression upon its withdrawal. To elucidate the molecular mediators of this paradox, tissue samples...

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Dades bibliogràfiques
Autors principals: Abukhdeir, Abde M., Vitolo, Michele I., Argani, Pedram, De Marzo, Angelo M., Karakas, Bedri, Konishi, Hiroyuki, Gustin, John P., Lauring, Josh, Garay, Joseph P., Pendleton, Courtney, Konishi, Yuko, Blair, Brian G., Brenner, Keith, Garrett-Mayer, Elizabeth, Carraway, Hetty, Bachman, Kurtis E., Park, Ben Ho
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224203/
https://ncbi.nlm.nih.gov/pubmed/18162533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710887105
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