Tamoxifen-stimulated growth of breast cancer due to p21 loss

Tamoxifen is widely used for the treatment of hormonally responsive breast cancers. However, some resistant breast cancers develop a growth proliferative response to this drug, as evidenced by tumor regression upon its withdrawal. To elucidate the molecular mediators of this paradox, tissue samples...

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Main Authors: Abukhdeir, Abde M., Vitolo, Michele I., Argani, Pedram, De Marzo, Angelo M., Karakas, Bedri, Konishi, Hiroyuki, Gustin, John P., Lauring, Josh, Garay, Joseph P., Pendleton, Courtney, Konishi, Yuko, Blair, Brian G., Brenner, Keith, Garrett-Mayer, Elizabeth, Carraway, Hetty, Bachman, Kurtis E., Park, Ben Ho
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2008
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224203/
https://ncbi.nlm.nih.gov/pubmed/18162533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710887105
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