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PROTON-COUPLED DYNAMICS IN LACTOSE PERMEASE
Lactose permease of Escherichia coli (LacY) catalyzes symport of a galactopyranoside and an H(+) via an alternating access mechanism. The transition from an inward- to an outward-facing conformation of LacY involves sugar-release followed by deprotonation. Because the transition depends intimately u...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496080/ https://ncbi.nlm.nih.gov/pubmed/23000385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.021 |
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