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A molecular mechanism for energy coupling in a membrane transport protein, the lactose permease of Escherichia coli

A mechanism for the coupled translocation of substrate and H(+) by the lactose permease of Escherichia coli is proposed, based on a variety of experimental observations. The permease is composed of 12 α-helical rods that traverse the membrane with the N and C termini on the cytoplasmic face. Four re...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Kaback, H. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20814/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9159108/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.11.5539
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