Lysomotropic amines cause intracellular accumulation of receptors for epidermal growth factor.

By direct biochemical methods, we demonstrate that the process of internalization of receptors for epidermal growth factor (EGF) occurs even without EGF stimulation and is not prevented by the lysomotopic agents methylamine or chloroquine. These agents inhibit the degradation of 125I-labeled EGF, th...

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Bibliografiske detaljer
Main Authors: King, A C, Hernaez-Davis, L, Cuatrecasas, P
Format: Artigo
Sprog:Inglês
Udgivet: 1980
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC349599/
https://ncbi.nlm.nih.gov/pubmed/6251452
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