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Lysosomotropic amines inhibit mitogenesis induced by growth factors.
The stimulation of DNA synthesis by epidermal growth factor, insulin, and serum is inhibited by a variety of alkylamines when present for the duration of the stimulatory preincubation (20-24 hr). These results contradict an earlier report [Maxfield, F. R., Davies, P. J. A., Klempner, L., Willingham,...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1981
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6262764/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.717 |
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