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Lysosomotropic amines inhibit mitogenesis induced by growth factors.

The stimulation of DNA synthesis by epidermal growth factor, insulin, and serum is inhibited by a variety of alkylamines when present for the duration of the stimulatory preincubation (20-24 hr). These results contradict an earlier report [Maxfield, F. R., Davies, P. J. A., Klempner, L., Willingham,...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: King, A C, Hernaez-Davis, L, Cuatrecasas, P
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1981
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319873/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6262764/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.717
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