Adenovirus E3 protein causes constitutively internalized epidermal growth factor receptors to accumulate in a prelysosomal compartment, resulting in enhanced degradation.

We have previously identified and characterized an integral membrane protein coded for by the early transcription region 3 (E3) of human group C adenoviruses that down-regulates the epidermal growth factor receptor (EGFR). The goal of this study was to characterize the early receptor trafficking eve...

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Detalles Bibliográficos
Main Authors: Hoffman, P, Carlin, C
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC358737/
https://ncbi.nlm.nih.gov/pubmed/8196613
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