Adenovirus E3 protein causes constitutively internalized epidermal growth factor receptors to accumulate in a prelysosomal compartment, resulting in enhanced degradation.
We have previously identified and characterized an integral membrane protein coded for by the early transcription region 3 (E3) of human group C adenoviruses that down-regulates the epidermal growth factor receptor (EGFR). The goal of this study was to characterize the early receptor trafficking eve...
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| Опубликовано в:: | Mol Cell Biol |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
1994
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358737/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8196613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.6.3695-3706.1994 |
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