Effect of cetiedil on erythrocyte sickling: new type of antisickling agent that may affect erythrocyte membranes.
The antisickling effect of cetiedil, alpha-cyclohexyl-3-thiopheneacetic acid 2-(hexahydro-1H-azepin-1-yl)-ethyl ester, has been investigated. The concentration of cetiedil required for 50% inhibition of erythrocyte sickling was about 140 micro M. An antisickling effect was achieved regardless of whe...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1980
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6930678/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2955 |
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