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Physiological and x-ray studies of potential antisickling agents.

Several aromatic compounds have been found to inhibit the gelling of sickle cell hemoglobin. We have tried to correlate the antigelling activity of such compounds with the stereo-chemistry of their binding sites in the hemoglobin molecule. This approach led to the discovery that two known antilipopr...

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Bibliografische gegevens
Hoofdauteurs: Abraham, D J, Perutz, M F, Phillips, S E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1983
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC393369/
https://ncbi.nlm.nih.gov/pubmed/6572894
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