Physiological and x-ray studies of potential antisickling agents.

Several aromatic compounds have been found to inhibit the gelling of sickle cell hemoglobin. We have tried to correlate the antigelling activity of such compounds with the stereo-chemistry of their binding sites in the hemoglobin molecule. This approach led to the discovery that two known antilipopr...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Abraham, D J, Perutz, M F, Phillips, S E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1983
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393369/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6572894/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.2.324
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