Effect of cetiedil on erythrocyte sickling: new type of antisickling agent that may affect erythrocyte membranes.

The antisickling effect of cetiedil, alpha-cyclohexyl-3-thiopheneacetic acid 2-(hexahydro-1H-azepin-1-yl)-ethyl ester, has been investigated. The concentration of cetiedil required for 50% inhibition of erythrocyte sickling was about 140 micro M. An antisickling effect was achieved regardless of whe...

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Bibliografiske detaljer
Main Authors: Asakura, T, Ohnishi, S T, Adachi, K, Ozguc, M, Hashimoto, K, Singer, M, Russell, M O, Schwartz, E
Format: Artigo
Sprog:Inglês
Udgivet: 1980
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC349525/
https://ncbi.nlm.nih.gov/pubmed/6930678
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