Effect of cetiedil on erythrocyte sickling: new type of antisickling agent that may affect erythrocyte membranes.

The antisickling effect of cetiedil, alpha-cyclohexyl-3-thiopheneacetic acid 2-(hexahydro-1H-azepin-1-yl)-ethyl ester, has been investigated. The concentration of cetiedil required for 50% inhibition of erythrocyte sickling was about 140 micro M. An antisickling effect was achieved regardless of whe...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Asakura, T, Ohnishi, S T, Adachi, K, Ozguc, M, Hashimoto, K, Singer, M, Russell, M O, Schwartz, E
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1980
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6930678/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2955
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