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Methotrexate polyglutamate synthesis by cultured human breast cancer cells.

We studied the conversion of methotrexate to poly-gamma-glutamyl derivatives by cultured human breast cancer cells. After incubation with 2 micro M [3',5',9-3H]methotrexate, MCF-7 cells were washed free of extracellular drug and were boiled to lyse cells and to release drug bound to dihydr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schilsky, R L, Bailey, B D, Chabner, B A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1980
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC349517/
https://ncbi.nlm.nih.gov/pubmed/6156458
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