Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response

CD8+ T cells are central to the eradication of intracellular pathogens, but they can also act to limit inflammation and immunopathology. During primary respiratory viral infection CD8+ effector T cells release the immunosuppressive cytokine IL-10, which is essential for host survival. Here we report...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Perona-Wright, Georgia, Kohlmeier, Jacob E., Bassity, Elizabeth, Freitas, Tori C., Mohrs, Katja, Cookenham, Tres, Situ, Haozhong, Pearce, Edward J., Woodland, David L., Mohrs, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494933/
https://ncbi.nlm.nih.gov/pubmed/23091017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119133109
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados