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Differential Regulation of IL-4Rα Expression by Antigen versus Cytokine Stimulation Characterizes Th2 Progression In Vivo

IL-4 promotes Th2 differentiation and provides immunity to helminth infections but is also associated with allergy and asthma. This suggests that precise adjustment of IL-4 responsiveness is needed to correctly balance immune responses. The IL-4Rα chain is an essential component of the IL-4 receptor...

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Detalhes bibliográficos
Main Authors: Perona-Wright, Georgia, Mohrs, Katja, Mayer, Katrin D., Mohrs, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066071/
https://ncbi.nlm.nih.gov/pubmed/20018622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902408
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