Systemic but not local infections elicit immunosuppressive IL-10 production by Natural Killer cells

IL-10 is an anti-inflammatory mediator, important in limiting immunopathology. Its impact is influenced both by the timing and localization of its release. Here we show that NK cells rapidly express IL-10 during acute infection with the rapidly disseminating pathogens Toxoplasma gondii, Listeria mon...

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Detalhes bibliográficos
Main Authors: Perona-Wright, Georgia, Mohrs, Katja, Szaba, Frank M., Kummer, Lawrence W., Madan, Rajat, Karp, Christopher L., Johnson, Lawrence L., Smiley, Stephen T., Mohrs, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796259/
https://ncbi.nlm.nih.gov/pubmed/20006839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2009.11.003
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