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A Two-Step Process for Cytokine Production Revealed by IL-4 Dual-Reporter Mice
To monitor IL-4 expression at the single-cell level, we generated mice with insertions of different reporter genes into both copies of the Il4 gene that permitted the simultaneous analysis of IL-4 transcripts using GFP and IL-4 protein secretion using human CD2. Both innate and adaptive cells compet...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826320/ https://ncbi.nlm.nih.gov/pubmed/16226507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2005.09.006 |
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