A Two-Step Process for Cytokine Production Revealed by IL-4 Dual-Reporter Mice

To monitor IL-4 expression at the single-cell level, we generated mice with insertions of different reporter genes into both copies of the Il4 gene that permitted the simultaneous analysis of IL-4 transcripts using GFP and IL-4 protein secretion using human CD2. Both innate and adaptive cells compet...

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Hauptverfasser: Mohrs, Katja, Wakil, Adil E., Killeen, Nigel, Locksley, Richard M., Mohrs, Markus
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826320/
https://ncbi.nlm.nih.gov/pubmed/16226507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2005.09.006
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