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Non-malignant clonal expansions of memory CD8(+) T cells that arise with age vary in their capacity to mount recall responses to infection
Immune responsiveness declines with age in part due to the development of CD8(+) T cell expansions (TCE) that can dominate the peripheral T cell pool. Although some TCE arise due to persistent antigen stimulation from chronic infections, others arise in the apparent absence of chronic infection. We...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933333/ https://ncbi.nlm.nih.gov/pubmed/20720204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001745 |
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