Early dysregulation of the memory CD8(+) T cell repertoire leads to compromised immune responses to secondary viral infection in the aged

BACKGROUND: Virus-specific memory CD8(+) T cells persist long after infection is resolved and are important for mediating recall responses to secondary infection. Although the number of memory T cells remains relatively constant over time, little is known about the overall stability of the memory T...

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Hlavní autoři: Connor, Lisa M, Kohlmeier, Jacob E, Ryan, Lynn, Roberts, Alan D, Cookenham, Tres, Blackman, Marcia A, Woodland, David L
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564731/
https://ncbi.nlm.nih.gov/pubmed/23244347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-9-28
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