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Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge

Memory CD8(+) T cells in the lung airways provide protection from secondary respiratory virus challenge by limiting early viral replication. Here, we demonstrate that although airway-resident memory CD8(+) T cells were poorly cytolytic, memory CD8(+) T cells recruited to the airways early during a r...

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Detalhes bibliográficos
Main Authors: Kohlmeier, Jacob E., Cookenham, Tres, Roberts, Alan D., Miller, Shannon C., Woodland, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908370/
https://ncbi.nlm.nih.gov/pubmed/20637658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.06.016
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