Loss of antigen cross-presentation after complete tumor resection is associated with the generation of protective tumor-specific CD8(+) T-cell immunity

An incomplete understanding on the effect of surgery on tumor-specific immunity continues to hamper efforts to combine surgery with immunotherapy in the clinic. Herein, we describe the impact of tumor resection on the tumor-specific T-cell response, showing that complete tumor resection is associate...

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Detalles Bibliográficos
Autores principales: Brown, Matthew D., van der Most, Robbert, Vivian, Justin B., Lake, Richard A., Larma, Irma, Robinson, Bruce W. S., Currie, Andrew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494622/
https://ncbi.nlm.nih.gov/pubmed/23170256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20924
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