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Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2
Hedgehog (Hh) signaling plays pivotal roles in embryonic development and adult tissue homeostasis in species ranging from Drosophila to mammals. The Hh signal is transduced by Smoothened (Smo), a seven-transmembrane protein related to G protein coupled receptors. Despite a conserved mechanism by whi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494391/ https://ncbi.nlm.nih.gov/pubmed/22986504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.134 |
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