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The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53
The p53 tumor suppressor is highly responsive to different physiological stresses such as abnormal cell proliferation, nutrient deprivation, and DNA damage. Distinct signaling mechanisms have evolved to activate p53, which in turn modulate numerous pathways to enhance fitness and survival of the org...
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| 1. autor: | |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
SAGE Publications
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494364/ https://ncbi.nlm.nih.gov/pubmed/23150760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912454733 |
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