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The PDZ Protein GIPC Regulates Trafficking of the LPA(1) Receptor from APPL Signaling Endosomes and Attenuates the Cell’s Response to LPA
Lysophosphatidic acid (LPA) mediates diverse cellular responses through the activation of at least six LPA receptors – LPA(1–6,) but the interacting proteins and signaling pathways that mediate the specificity of these receptors are largely unknown. We noticed that LPA(1) contains a PDZ binding moti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493537/ https://ncbi.nlm.nih.gov/pubmed/23145131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049227 |
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