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The PDZ Protein GIPC Regulates Trafficking of the LPA(1) Receptor from APPL Signaling Endosomes and Attenuates the Cell’s Response to LPA

Lysophosphatidic acid (LPA) mediates diverse cellular responses through the activation of at least six LPA receptors – LPA(1–6,) but the interacting proteins and signaling pathways that mediate the specificity of these receptors are largely unknown. We noticed that LPA(1) contains a PDZ binding moti...

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Bibliografski detalji
Glavni autori: Varsano, Tal, Taupin, Vanessa, Guo, Lixia, Baterina, Oscar Y., Farquhar, Marilyn G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493537/
https://ncbi.nlm.nih.gov/pubmed/23145131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049227
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