Distinct Effects on Diversifying Selection by Two Mechanisms of Immunity against Streptococcus pneumoniae

Antigenic variation to evade host immunity has long been assumed to be a driving force of diversifying selection in pathogens. Colonization by Streptococcus pneumoniae, which is central to the organism's transmission and therefore evolution, is limited by two arms of the immune system: antibody...

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Autors principals: Li, Yuan, Gierahn, Todd, Thompson, Claudette M., Trzciński, Krzysztof, Ford, Christopher B., Croucher, Nicholas, Gouveia, Paulo, Flechtner, Jessica B., Malley, Richard, Lipsitch, Marc
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493470/
https://ncbi.nlm.nih.gov/pubmed/23144610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002989
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